Q3 2025 Holdings
Filed 2025-11-17 | 40 holdings | $2.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Abivax SA American Depositary Shares(ABVX) | ADRS | 00370M103 | $603.8M | 7,111,596 | 29.7% |
| CG Oncology Inc(CGON) | COMM | 156944100 | $147.8M | 3,670,206 | 7.3% |
| Cogent Biosciences Inc(COGT) | COMM | 19240Q201 | $97.6M | 6,798,162 | 4.8% |
| Amylyx Pharmaceuticals Inc(AMLX) | COMM | 03237H101 | $84.9M | 6,243,812 | 4.2% |
| Centessa Pharmaceuticals PLC(CNTA) | ADRS | 152309100 | $76.1M | 3,136,480 | 3.7% |
| Tango Therapeutics Inc(TNGX) | COMM | 87583X109 | $71.7M | 8,536,196 | 3.5% |
| Ocular Therapeutix Inc(OCUL) | COMM | 67576A100 | $71.5M | 6,117,232 | 3.5% |
| Dianthus Therapeutics Inc(DNTH) | COMM | 252828108 | $66.0M | 1,676,624 | 3.2% |
| Tourmaline BIO Inc(TRML) | COMM | 89157D105 | $62.7M | 1,311,783 | 3.1% |
| Dyne Therapeutics Inc(DYN) | COMM | 26818M108 | $58.4M | 4,615,144 | 2.9% |
| Agios Pharmaceuticals Inc(AGIO) | COMM | 00847X104 | $57.4M | 1,430,041 | 2.8% |
| Eyepoint Pharmaceuticals Inc(EYPT) | COMM | 30233G209 | $50.9M | 3,572,335 | 2.5% |
| Fulcrum Therapeutics Inc(FULC) | COMM | 359616109 | $48.3M | 5,250,000 | 2.4% |
| Savara Inc(SVRA) | COMM | 805111101 | $44.1M | 12,362,205 | 2.2% |
| Rapt Therapeutics Inc(RAPT) | COMM | 75382E208 | $42.2M | 1,636,275 | 2.1% |
| Tyra Biosciences Inc(TYRA) | COMM | 90240B106 | $40.5M | 2,898,103 | 2.0% |
| Upstream BIO Inc(UPB) | COMM | 91678A107 | $39.8M | 2,117,103 | 2.0% |
| Liquidia Technologies Inc(LQDA) | COMM | 53635D202 | $38.9M | 1,710,084 | 1.9% |
| Disc Medicine Inc(IRON) | COMM | 254604101 | $30.7M | 465,257 | 1.5% |
| Structure Therapeutics Inc(GPCR) | ADRS | 86366E106 | $29.8M | 1,063,000 | 1.5% |
| Xencor Inc(XNCR) | COMM | 98401F105 | $28.8M | 2,452,138 | 1.4% |
| LB Pharmaceuticals Inc(LBRX) | COMM | 50180M108 | $27.6M | 1,745,016 | 1.4% |
| Revolution Medicines Inc(RVMD) | COMM | 76155X100 | $20.4M | 436,473 | 1.0% |
| Astria Therapeutics Inc(CATBUSD) | COMM | 04635X102 | $20.1M | 2,761,861 | 1.0% |
| Korro BIO Inc(KRRO) | COMM | 500946108 | $19.9M | 416,301 | 1.0% |
| Kodiak Sciences Inc(KOD) | COMM | 50015M109 | $18.8M | 1,145,538 | 0.9% |
| Spyre Therapeutics Inc(SYRE) | COMM | 00773J202 | $18.4M | 1,100,582 | 0.9% |
| Silence Therapeutics PLC(SLN) | ADRS | 82686Q101 | $15.7M | 3,033,560 | 0.8% |
| Urogen Pharma LTD(URGN) | COMM | M96088105 | $14.3M | 717,347 | 0.7% |
| Arvinas Holding Co LLC(ARVN) | COMM | 04335A105 | $13.8M | 1,617,365 | 0.7% |
| Monopar Therapeutics Inc(MNPR) | COMM | 61023L207 | $12.5M | 153,000 | 0.6% |
| MBX Biosciences Inc(MBX) | COMM | 55287L101 | $11.4M | 650,000 | 0.6% |
| Vistagen Therapeutics Inc(VTGN) | COMM | 92840H400 | $9.5M | 2,676,580 | 0.5% |
| Relay Therapeutics Inc(RLAY) | COMM | 75943R102 | $9.5M | 1,810,351 | 0.5% |
| Adverum Biotechnologies Inc(AVU0) | COMM | 00773U207 | $7.6M | 1,668,174 | 0.4% |
| Avalo Therapeutics Inc(AVTX) | COMM | 05338F306 | $6.1M | 483,000 | 0.3% |
| ADC Therapeutics SA(ADCT) | COMM | H0036K147 | $5.6M | 1,390,175 | 0.3% |
| Pepgen Inc(PEPG) | COMM | 713317105 | $5.5M | 1,200,000 | 0.3% |
| Entrada Therapeutics Inc(TRDA) | COMM | 29384C108 | $3.4M | 584,955 | 0.2% |
| Ventyx Biosciences Inc(VTYX) | COMM | 92332V107 | $983.4K | 316,195 | 0.0% |