Q4 2025 Holdings
Filed 2026-02-17 | 27 holdings | $2.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
Sign in to see sub-manager breakdown
| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $641.1M | 8,493,321 | 31.7% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $125.7M | 4,148,428 | 6.2% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $120.8M | 3,882,709 | 6.0% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $120.7M | 3,685,448 | 6.0% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $108.7M | 6,728,985 | 5.4% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $88.8M | 7,315,547 | 4.4% |
| Savara Inc(SVRA) | COM | 805111101 | $82.9M | 13,740,375 | 4.1% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $71.0M | 2,000,000 | 3.5% |
| Erasca Inc(ERAS) | COM | 29479A108 | $66.4M | 17,857,083 | 3.3% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $66.3M | 15,561,500 | 3.3% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $64.2M | 1,548,569 | 3.2% |
| Jade Biosciences Inc(JBIO) | COM NEW | 008064206 | $49.7M | 3,220,364 | 2.5% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $49.7M | 3,226,331 | 2.5% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $46.4M | 5,676,230 | 2.3% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $43.1M | 4,771,414 | 2.1% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $42.5M | 2,173,913 | 2.1% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $41.2M | 1,000,000 | 2.0% |
| Upstream BIO Inc(UPB) | COM | 91678A107 | $31.7M | 1,169,298 | 1.6% |
| Cybin Inc(HELP) | COM NEW | 23256X407 | $31.4M | 3,840,250 | 1.6% |
| Zura BIO LTD(ZURA) | CLASS A ORD SHS | G9TY5A101 | $28.0M | 5,345,115 | 1.4% |
| VOR Biopharma Inc(VOR) | COM NEW | 929033207 | $25.4M | 1,943,766 | 1.3% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $25.3M | 2,133,576 | 1.2% |
| Septerna Inc(SEPN) | COM | 81734D104 | $17.0M | 610,808 | 0.8% |
| Surrozen Inc(SRZN) | COM NEW | 86889P208 | $14.3M | 632,931 | 0.7% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $14.3M | 1,379,965 | 0.7% |
| Artiva Biotherapeutics Inc(ARTV) | COM | 04317A107 | $6.9M | 1,609,569 | 0.3% |
| Casi Pharmaceuticals Inc(CASIF) | ORD SHS | G1933S101 | $839.2K | 987,259 | 0.0% |