Q2 2025 Holdings
Filed 2025-08-14 | 66 holdings | $3.1B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Guardant Health Inc(GH) | COM | 40131M109 | $221.2M | 4,250,000 | 7.1% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $193.3M | 4,891,544 | 6.2% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $179.4M | 3,245,899 | 5.8% |
| Dynavax Technologies Corp(DVAX) | COM NEW | 268158201 | $176.5M | 17,791,486 | 5.7% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $176.1M | 1,750,000 | 5.6% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $162.4M | 3,042,598 | 5.2% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $152.0M | 9,500,000 | 4.9% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $132.7M | 14,294,420 | 4.3% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $121.2M | 7,000,000 | 3.9% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $120.6M | 3,650,000 | 3.9% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $106.5M | 5,133,917 | 3.4% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $93.3M | 9,500,000 | 3.0% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $83.7M | 801,371 | 2.7% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $75.2M | 5,380,449 | 2.4% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $70.9M | 1,750,000 | 2.3% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $69.9M | 2,150,000 | 2.2% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $69.1M | 6,064,910 | 2.2% |
| Geron Corp(GERN) | COM | 374163103 | $60.6M | 43,000,000 | 1.9% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $56.5M | 1,800,000 | 1.8% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $49.1M | 1,350,000 | 1.6% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $48.5M | 3,948,910 | 1.6% |
| ANI Pharmaceuticals Inc(ANIP) | COM | 00182C103 | $45.7M | 700,000 | 1.5% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $42.3M | 1,350,000 | 1.4% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $41.6M | 2,233,148 | 1.3% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $40.7M | 2,000,000 | 1.3% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $38.9M | 900,000 | 1.2% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $38.4M | 16,852,147 | 1.2% |
| Metsera Inc | COM | 59267L107 | $31.1M | 1,094,408 | 1.0% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $28.0M | 7,495,000 | 0.9% |
| Tectonic Therapeutic Inc(TECX) | COM | 878972108 | $27.9M | 1,401,938 | 0.9% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $26.6M | 3,480,144 | 0.9% |
| Jade Biosciences Inc(JBIO) | COM NEW | 008064206 | $25.1M | 2,509,301 | 0.8% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $25.0M | 2,188,592 | 0.8% |
| Compass Pathways PLC(CMPS) | SPONSORED ADS | 20451W101 | $24.7M | 8,831,007 | 0.8% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $24.4M | 2,000,000 | 0.8% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $22.5M | 2,426,657 | 0.7% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $21.5M | 1,918,798 | 0.7% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $16.6M | 4,557,575 | 0.5% |
| Mind Medicine Mindmed Inc(BRD1EUR) | COM NEW | 60255C885 | $16.2M | 2,500,000 | 0.5% |
| Upstream BIO Inc(UPB) | COM | 91678A107 | $15.8M | 1,442,767 | 0.5% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $14.7M | 3,442,833 | 0.5% |
| Merus N V | COM | N5749R100 | $14.5M | 275,000 | 0.5% |
| Cybin Inc(HELP) | COM NEW | 23256X407 | $12.8M | 1,529,987 | 0.4% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $12.2M | 250,000 | 0.4% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $8.4M | 1,203,244 | 0.3% |
| Sarepta Therapeutics Inc(SRPT)Put | COM | 803607100 | $7.7M | 450,000 | 0.2% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $7.3M | 453,686 | 0.2% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $6.6M | 500,000 | 0.2% |
| Novavax Inc(NVAX) | COM NEW | 670002401 | $6.3M | 998,542 | 0.2% |
| Invivyd Inc(IVVD) | COM | 00534A102 | $6.1M | 8,585,980 | 0.2% |