Q4 2024 Holdings
Filed 2025-02-18 | 50 holdings | $2.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $409.1M | 15,916,418 | 17.0% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $271.7M | 6,570,392 | 11.3% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $157.2M | 3,383,950 | 6.5% |
| Krystal Biotech Inc(KRYS) | COM | 501147102 | $123.5M | 788,460 | 5.1% |
| Arcutis Biotherapeutics Inc(ARQT) | COM | 03969K108 | $122.4M | 8,785,284 | 5.1% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $111.3M | 1,754,834 | 4.6% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $110.3M | 5,985,347 | 4.6% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $104.7M | 1,869,808 | 4.3% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $104.3M | 3,800,457 | 4.3% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $87.9M | 1,587,527 | 3.6% |
| Phathom Pharmaceuticals Inc(PHAT) | COM | 71722W107 | $82.1M | 10,109,279 | 3.4% |
| Erasca Inc(ERAS) | COM | 29479A108 | $48.7M | 19,391,687 | 2.0% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $44.2M | 539,405 | 1.8% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $43.9M | 10,664,774 | 1.8% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $43.6M | 997,455 | 1.8% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $41.4M | 4,887,867 | 1.7% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $35.2M | 1,069,754 | 1.5% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $33.9M | 1,271,245 | 1.4% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $31.4M | 699,159 | 1.3% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $31.4M | 3,888,238 | 1.3% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $27.7M | 658,715 | 1.2% |
| Savara Inc(SVRA) | COM | 805111101 | $26.6M | 8,660,379 | 1.1% |
| CG Oncology Inc(CGON) | COM | 156944100 | $22.1M | 770,000 | 0.9% |
| Hillevax Inc | COM | 43157M102 | $22.0M | 10,617,062 | 0.9% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $20.8M | 1,573,719 | 0.9% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $18.6M | 1,479,025 | 0.8% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $18.4M | 133,333 | 0.8% |
| Mereo Biopharma Group PLC(MREO) | SPON ADS | 589492107 | $17.8M | 5,097,779 | 0.7% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $17.3M | 601,129 | 0.7% |
| Merus N V | COM | N5749R100 | $15.7M | 373,100 | 0.7% |
| Immatics N.v(IMTX) | SHS | N44445109 | $15.3M | 2,147,911 | 0.6% |
| Pliant Therapeutics Inc(PLRX) | COM | 729139105 | $14.8M | 1,120,803 | 0.6% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $12.1M | 1,953,547 | 0.5% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $11.3M | 583,327 | 0.5% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $10.9M | 4,623,324 | 0.5% |
| Macrogenics Inc(MGNX) | COM | 556099109 | $10.3M | 3,175,665 | 0.4% |
| DAY One Biopharmaceuticals I(DAWN) | COM | 23954D109 | $8.7M | 689,655 | 0.4% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $8.6M | 470,338 | 0.4% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $7.9M | 1,148,591 | 0.3% |
| Palvella Therapeutics Inc NE(PVLA) | COM | 697947109 | $7.8M | 653,892 | 0.3% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $7.8M | 1,000,000 | 0.3% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $7.3M | 936,576 | 0.3% |
| Newamsterdam Pharma Company | *W EXP 99/99/999 | N62509117 | $7.1M | 500,333 | 0.3% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $6.3M | 955,515 | 0.3% |
| Allogene Therapeutics Inc(ALLO) | COM | 019770106 | $6.1M | 2,867,750 | 0.3% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $5.5M | 285,331 | 0.2% |
| Adverum Biotechnologies Inc(AVU0) | COM NEW | 00773U207 | $5.0M | 1,069,244 | 0.2% |
| Eledon Pharmaceuticals Inc(ELDN) | COM | 28617K101 | $4.8M | 1,176,735 | 0.2% |
| Elevation Oncology Inc | COM | 28623U101 | $3.4M | 5,993,579 | 0.1% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $3.2M | 108,762 | 0.1% |