Q4 2024 Holdings
Filed 2025-02-14 | 99 holdings | $3.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $296.8M | 6,392,106 | 8.2% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $266.8M | 3,478,888 | 7.4% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $228.4M | 24,245,952 | 6.3% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $206.0M | 3,680,473 | 5.7% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $205.1M | 2,619,977 | 5.7% |
| Iovance Biotherapeutics Inc(IOVA) | COM | 462260100 | $163.6M | 22,112,266 | 4.5% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $140.7M | 1,718,417 | 3.9% |
| Intra-Cellular Therapies Inc(ITCIEUR) | COM | 46116X101 | $107.6M | 1,288,328 | 3.0% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $106.3M | 6,349,220 | 2.9% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $102.3M | 1,329,735 | 2.8% |
| Artivion Inc(AORT) | COM | 228903100 | $79.9M | 2,793,703 | 2.2% |
| Meiragtx Hldgs PLC(MGTX) | COM | G59665102 | $76.6M | 12,581,103 | 2.1% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $71.7M | 2,685,537 | 2.0% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $67.5M | 1,501,040 | 1.9% |
| Immatics N.v(IMTX) | SHS | N44445109 | $66.7M | 9,383,456 | 1.8% |
| Insulet Corp(PODD) | COM | 45784P101 | $60.6M | 232,269 | 1.7% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $59.9M | 2,574,723 | 1.7% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $58.0M | 6,485,420 | 1.6% |
| Evolus Inc(EOLS) | COM | 30052C107 | $56.8M | 5,145,846 | 1.6% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $56.2M | 664,074 | 1.5% |
| Cargo Therapeutics Inc(CRGX) | COM | 14179K101 | $53.1M | 3,683,004 | 1.5% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $53.0M | 2,139,199 | 1.5% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $49.1M | 1,271,662 | 1.4% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $47.4M | 1,047,232 | 1.3% |
| Aldeyra Therapeutics Inc(ALDX) | COM | 01438T106 | $46.3M | 9,275,851 | 1.3% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $43.8M | 817,895 | 1.2% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $41.5M | 67,471 | 1.1% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $40.1M | 995,894 | 1.1% |
| Praxis Precision Medicines I(PRAX)Call | COM NEW | 74006W207 | $38.5M | 500,000 | 1.1% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $33.0M | 1,185,592 | 0.9% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $32.9M | 63,119 | 0.9% |
| Acrivon Therapeutics Inc(ACRV) | COMMON STOCK | 004890109 | $32.3M | 5,360,858 | 0.9% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $31.2M | 2,130,020 | 0.9% |
| Celcuity Inc(CELC) | COM | 15102K100 | $30.9M | 2,362,279 | 0.9% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $28.5M | 1,486,508 | 0.8% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $27.6M | 6,906,646 | 0.8% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $25.6M | 6,774,348 | 0.7% |
| Procept Biorobotics Corp(PRCT) | COM | 74276L105 | $23.4M | 290,659 | 0.6% |
| Nautilus Biotechnology Inc(NAUT) | COM | 63909J108 | $21.2M | 12,594,211 | 0.6% |
| Contineum Therapeutics Inc(CTNM) | CL A | 21217B100 | $21.1M | 1,441,249 | 0.6% |
| Natera Inc(NTRA) | COM | 632307104 | $19.8M | 125,000 | 0.5% |
| Inhibikase Therapeutics Inc(IKT) | COM NEW | 45719W205 | $19.3M | 5,925,000 | 0.5% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $18.4M | 4,592,556 | 0.5% |
| Penumbra Inc(PEN) | COM | 70975L107 | $17.4M | 73,338 | 0.5% |
| Septerna Inc(SEPN) | COM | 81734D104 | $17.2M | 750,000 | 0.5% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $16.4M | 845,567 | 0.5% |
| Inhibrx Biosciences Inc(INBX) | COM | 45720N103 | $16.4M | 1,064,026 | 0.5% |
| Adma Biologics Inc(ADMA) | COM | 000899104 | $15.3M | 890,280 | 0.4% |
| Bright Minds Biosciences Inc(DRUG) | COM NEW | 10919W405 | $14.5M | 403,649 | 0.4% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $14.2M | 740,749 | 0.4% |