Q2 2025 Holdings
Filed 2025-08-13 | 111 holdings | $1.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Scholar Rock Holding Corp(SRRK) | COM | 80706P103 | $327.6M | 9,250,005 | 17.0% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $149.6M | 3,428,150 | 7.7% |
| BeOne Medicines AG(ONC) | SPONSORED ADS | 07725L102 | $123.5M | 509,990 | 6.4% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $58.2M | 1,099,401 | 3.0% |
| Crinetics Pharmaceuticals Inc(CRNX) | COM | 22663K107 | $48.6M | 1,688,611 | 2.5% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $48.5M | 5,216,969 | 2.5% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $46.0M | 4,836,437 | 2.4% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $45.5M | 3,460,029 | 2.4% |
| Merus NV | COM | N5749R100 | $44.9M | 853,467 | 2.3% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $44.6M | 2,578,396 | 2.3% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $42.4M | 245,943 | 2.2% |
| Arrowhead Pharmaceuticals Inc(ARWR) | COM | 04280A100 | $42.2M | 2,669,880 | 2.2% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $41.4M | 3,160,298 | 2.1% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $39.2M | 467,342 | 2.0% |
| Lexicon Pharmaceuticals Inc(LXRX) | COM NEW | 528872302 | $36.8M | 38,918,903 | 1.9% |
| Taboola.com Ltd(TBLA) | ORD SHS | M8744T106 | $36.5M | 9,969,495 | 1.9% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $36.1M | 7,415,905 | 1.9% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $34.5M | 938,755 | 1.8% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $31.5M | 1,110,610 | 1.6% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $25.9M | 409,742 | 1.3% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $25.8M | 594,994 | 1.3% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $25.5M | 2,247,347 | 1.3% |
| Taysha Gene Therapies Inc(TSHA) | COM SHS | 877619106 | $25.4M | 11,014,737 | 1.3% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $25.4M | 812,761 | 1.3% |
| Wave Life Sciences Ltd(WVE) | SHS | Y95308105 | $24.0M | 3,696,322 | 1.2% |
| MoonLake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $24.0M | 508,267 | 1.2% |
| Septerna Inc(SEPN) | COM | 81734D104 | $23.3M | 2,202,514 | 1.2% |
| NewAmsterdam Pharma Company NV(NAMS) | ORDINARY SHARES | N62509109 | $21.6M | 1,194,240 | 1.1% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $21.5M | 3,938,793 | 1.1% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $17.2M | 3,364,814 | 0.9% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $17.0M | 318,647 | 0.9% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $16.9M | 2,911,438 | 0.9% |
| Arrivent Biopharma Inc(AVBP) | COM | 04272N102 | $15.2M | 700,000 | 0.8% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $14.0M | 2,012,752 | 0.7% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $13.1M | 1,612,077 | 0.7% |
| IHS Holding Limited(IHS) | ORD SHS | G4701H109 | $13.1M | 2,357,520 | 0.7% |
| Amazon.com Inc(AMZN) | COM | 023135106 | $12.4M | 56,500 | 0.6% |
| Denali Therapeutics Inc(DNLI) | COM | 24823R105 | $11.5M | 821,513 | 0.6% |
| Erasca Inc(ERAS) | COM | 29479A108 | $11.1M | 8,757,249 | 0.6% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $10.2M | 1,007,575 | 0.5% |
| Remitly Global Inc(RELY) | COM | 75960P104 | $9.7M | 515,449 | 0.5% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $9.6M | 295,543 | 0.5% |
| CrowdStrike Holdings Inc(CRWD) | CL A | 22788C105 | $9.4M | 18,500 | 0.5% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $9.0M | 1,193,410 | 0.5% |
| Alphabet Inc(GOOGL) | CAP STK CL A | 02079K305 | $8.9M | 50,703 | 0.5% |
| Upstream Bio Inc(UPB) | COM | 91678A107 | $8.7M | 788,450 | 0.4% |
| Seer Inc(SEER) | COM CL A | 81578P106 | $8.6M | 4,000,000 | 0.4% |
| Microsoft Corp(MSFT) | COM | 594918104 | $8.0M | 16,150 | 0.4% |
| Nvidia Corp(NVDA) | COM | 67066G104 | $7.9M | 49,985 | 0.4% |
| Ionq Inc(IONQ) | COM | 46222L108 | $7.3M | 170,000 | 0.4% |